Stem Cells in the 4th Dimension: Mechanisms of Stem Cell Aging and Maturation

April 13, 2016

BioPharmaceutical Technology Center
5445 East Cheryl Parkway
Fitchburg/Madison, WI 53711


OVERVIEW: The Symposium is coordinated by the Stem Cell & Regenerative Medicine Center, at the University of Wisconsin-Madison and the BTC Institute. It will bring together leading researchers investigating the effects of aging on stem cell populations and their progeny and recapitulating aging mechanisms in vitro to mature human stem cell derivatives and transplants. The morning session will review systemic and cell autonomous factors known to impact stem cell maturation, aging and senescence. The afternoon session will focus on using these approaches and understanding to develop in vitro models of matured, stem cell-derived neural, cardiac, and pancreatic cells and tissues for regenerative medicine applications.


  • Endocrine, micro-RNA, epigenetic, and metabolic regulators of aging
  • Systemic regulators elucidated by parabiosis
  • Treatment of age-related stem cell dysfunction
  • In vivo and in vitro models of neural, musculoskeletal, cardiac, and pancreatic tissue maturation


Craig Atwood, Ph.D., Associate Professor, Department of Medicine, Division of Geriatrics & Gerontology, Veterans Administration Hospital, University of Wisconsin–Madison, Madison, WI

Barak Blum, Ph.D., Assistant Professor, Department of Cell & Regenerative Biology, University of Wisconsin–Madison, Madison, WI

Vincent Chen, M.D., Ph.D., Professor, Department of Medicine Clinical Cardiac Electrophysiologist, Division of Cardiovascular Medicine, University of California, San Diego, La Jolla, CA

Paul Robbins, Ph.D., Professor, Department of Metabolism & Aging, Scripps Florida, The Scripps Research Institute, Jupiter, FL

Hannele Ruohola-Baker, Ph.D., Associate Director, Institute for Stem Cell and Regenerative Medicine; Professor, Department of Biochemistry, University of Washington, Seattle, WA

Lorenz Studer, M.D., Ph.D., Director, Sloan-Kettering Center for Stem Cell Biology; Professor, Department of Neuroscience, Weill-Cornell Graduate School, New York, NY

Rocky S. Tuan, Ph.D., Director, Center for Cellular and Molecular Engineering; Arthur J. Rooney, Sr. Professor and Executive Vice Chair, Department of Orthopaedic Surgery; Associate Director, McGowan Institute for Regenerative Medicine; Director, Center for Military Medicine Research; Professor, Departments of Bioengineering and Mechanical Engineering & Materials Science, University of Pittsburgh, Pittsburgh, PA

Tony Wyss-Coray, Ph.D., Professor, Neurology & Neurological Sciences, Stanford University School of Medicine; Associate Director, Center for Tissue Regeneration, Repair, and Restoration, Veterans Administration Palo Alto Health Care System, Palo Alto, CA




HOTELS: Blocks of rooms have been reserved for Symposium attendees at the following area hotels (cut-off dtaes in []): Clarion Suites at the Alliant Energy Center [3/13]; Country Inn & Suites Madison SW (Fitchburg)[3/12]; Graduate Madison [3/13]; Sheraton Madison Hotel [3/12]; Wyndham Garden [3/12].
Please be sure to refer to this event and to ask for the corresponding BTC Institute rates when you make your reservation.

2015 Symposium Summary
2014 Symposium Summary

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