Engineering Limb Regeneration

Recapitulating Normal Development and Regeneration

April 22, 2015

BioPharmaceutical Technology Center
5445 East Cheryl Parkway
Fitchburg/Madison, WI 53711

OVERVIEW: The Symposium is coordinated by the the Stem Cell & Regenerative Medicine Center, at the University of Wisconsin-Madison, and the BTC Institute. It brings together leading researchers who are working in the areas of limb development and regeneration (morning session) and stem cells and tissue engineering (afternoon session).


  • Historical perspectives on limb regeneration
  • The ability of amphibians to regenerate limbs and the relationships/differences of this to vertebrates
  • The role of epigenetic modifications that support or suppress limb regeneration in anurans and the relationships/differences of this to vertebrates
  • Epigenetic modifications that support or suppress regenerative potentail in the terminal phalanx of a mouse
  • Engineering/regeneration of specific tissues in a limb, e.g. cartilage, tendon and bone tissue engineering; skeletal muscle regeneration; priming mesenchymal stem cells for differentiation


Jeremy Brockes, Ph.D. (MRC Research Professor, Research Department of Structural and Molecular Biology, University College London, London, UK)

David Butler, Ph.D. (Professor, Biomedical Engineering, University of Cincinnati, Cincinnati, OH)

Johnny Huard, Ph.D. (Professor, Departments of Orthopaedic Surgery, Microbiology and Molecular Genetics, Bioengineering, Pathology, Pediatrics, and Physical Medicine and Rehabilitation; Director of the Stem Cell Research Center, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA )

Mayumi Ito, Ph.D. (Assistant Professor of Dermatoloy, Smilow Research Center, New York University Langone Medical Center, New York, NY)

Wan-ju Li (Assistant Professor, Department of Orthopedics and Rehabilitation, University of Wisconsin School of Medicine and Public Health, Madison, WI)

Helen Lu, Ph.D. (Professor of Biomedical Engineering, Columbia Engineering, Columbia University, New York, NY)

William Murphy, Ph.D. (Harvey D. Spangler Professor, Biomedical Engineering, College of Engineering, University of Wisconsin-Madison, Madison, WI)

David Stocum, Ph.D. (Professor and Dean Emeritus, Department of Biology, Indiana University-Purdue University Indianopolis, Indianapolis, IN)

Koji Tamura, Ph.D. (Professor, Laboratory of Organ Morphogenesis, Department of Developmental Biology and Neurosciences, Graduate School of Life Sciences, Tohoku University, Sendai, Japan)

Panagiotis Tsonis, Ph.D. (Professor, College of Arts and Sciences: Biology, and School of Engineering: Bioengineering Graduate Program; Dircector, Center for Tissue Regeneration and Engineering, University of Dayton, Dayton, OH)

2014 Symposium Summary
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