WISCONSIN STEM CELL SYMPOSIUM

Image courtesy of Carlos Marti-Figueroa, Wisconsin Institute for Discovery, University of Wisconsin-Madison


Stem Cells in the 4th Dimension:
Mechanisms of Stem Cell Aging and Maturation

HELD: April 13, 2016

BioPharmaceutical Technology Center
5445 East Cheryl Parkway
Fitchburg/Madison, WI 53711

MAP & DIRECTIONS

OVERVIEW: The Symposium was coordinated by the Stem Cell & Regenerative Medicine Center, at the University of Wisconsin-Madison and the BTC Institute. It brought together leading researchers investigating the effects of aging on stem cell populations and their progeny and recapitulating aging mechanisms in vitro to mature human stem cell derivatives and transplants. The morning session talks reviewed systemic and cell autonomous factors known to impact stem cell maturation, aging and senescence. The afternoon session focused on using these approaches and understanding to develop in vitro models of matured, stem cell-derived neural, cardiac, and pancreatic cells and tissues for regenerative medicine applications.

HIGHLIGHTED ISSUES:

  • Endocrine, micro-RNA, epigenetic, and metabolic regulators of aging
  • Systemic regulators elucidated by parabiosis
  • Treatment of age-related stem cell dysfunction
  • In vivo and in vitro models of neural, musculoskeletal, cardiac, and pancreatic tissue maturation

PRESENTERS

Craig Atwood, Ph.D., Associate Professor, Department of Medicine, Division of Geriatrics & Gerontology, Veterans Administration Hospital, University of Wisconsin–Madison, Madison, WI

Barak Blum, Ph.D., Assistant Professor, Department of Cell & Regenerative Biology, University of Wisconsin–Madison, Madison, WI

Vincent Chen, M.D., Ph.D., Professor, Department of Medicine Clinical Cardiac Electrophysiologist, Division of Cardiovascular Medicine, University of California, San Diego, La Jolla, CA

Paul Robbins, Ph.D., Professor, Department of Metabolism & Aging, Scripps Florida, The Scripps Research Institute, Jupiter, FL

Hannele Ruohola-Baker, Ph.D., Associate Director, Institute for Stem Cell and Regenerative Medicine; Professor, Department of Biochemistry, University of Washington, Seattle, WA

Lorenz Studer, M.D., Ph.D., Director, Sloan-Kettering Center for Stem Cell Biology; Professor, Department of Neuroscience, Weill-Cornell Graduate School, New York, NY

Rocky S. Tuan, Ph.D., Director, Center for Cellular and Molecular Engineering; Arthur J. Rooney, Sr. Professor and Executive Vice Chair, Department of Orthopaedic Surgery; Associate Director, McGowan Institute for Regenerative Medicine; Director, Center for Military Medicine Research; Professor, Departments of Bioengineering and Mechanical Engineering & Materials Science, University of Pittsburgh, Pittsburgh, PA

Tony Wyss-Coray, Ph.D., Professor, Neurology & Neurological Sciences, Stanford University School of Medicine; Associate Director, Center for Tissue Regeneration, Repair, and Restoration, Veterans Administration Palo Alto Health Care System, Palo Alto, CA

MODERATORS

Randolph S. Ashton Ph.D., Assistant Professor, Biomedical Engineering, University of Wisconsin–Madison, Madison, WI (Afternoon Session)

Craig Atwood, Ph.D., Associate Professor, Department of Medicine, Division of Geriatrics & Gerontology, Veterans Administration Hospital, University of Wisconsin–Madison, Madison, WI (Morning Session)

Timothy J. Kamp, M.D., Professor, Medicine; Co-director, Stem Cell and Regenerative Medicine Center, University of Wisconsin–Madison, Madison, WI (Welcome)

William L. Murphy, Ph.D., Professor, Biomedical Engineering, Orthopedics & Rehabilitation; Co-director, Stem Cell & Regenerative Medicine Center, University of Wisconsin–Madison, Madison, WI (Presentation of Poster Awards & Closing Remarks)

ABSTRACTS

SCHEDULE

POSTER SESSION ABSTRACTS
Congratulations to our three contest winners: 1st Place: Andrew Kahlil; 2nd Place: Xiaoping Bao; 3rd Place: Angela Xie. Thank you to all of our poster presenters -- excellent work!

2015 Symposium Summary
2014 Symposium Summary

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